COMPOSITIONS AND METHODS FOR EXPRESSING RECOMBINANT POLYPEPTIDES

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20160251410A1
SERIAL NO

14914003

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods of expressing a recombinant polypeptide of interest are provided. Accordingly there is provided a method comprising providing a cell having been contacted with an agent which downregulates an expression of a tuberous sclerosis (TSC) protein or directly inhibits an activity of same; and contacting the cell with a polynucleotide encoding the recombinant polypeptide of interest. Also provided is a method comprising contacting a cell with an agent which downregulates expression of a tuberous sclerosis (TSC) protein or directly inhibits an activity of same; and a polynucleotide encoding the recombinant polypeptide of interest. Also provided are isolated cells, cell cultures and articles of manufacture for recombinant expression of a recombinant polypeptide of interest.

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Patent Owner(s)

Patent OwnerAddress
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD5262000 RAMAT GAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DADIANI, Maya Rehovot, IL 2 6
TIROSH, Boaz Mevasseret Zion, IL 9 162

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