Cationic oil-in-water emulsions

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United States of America Patent

PATENT NO 10238733
APP PUB NO 20160256541A1
SERIAL NO

15067216

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Abstract

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This invention generally relates to cationic oil-in-water emulsions that can be used to deliver negatively charged molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are particularly suitable for delivering nucleic acid molecules (such as an RNA molecule encoding an antigen) to cells and formulating nucleic acid-based vaccines.

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Patent Owner(s)

  • GLAXOSMITHKLINE BIOLOGICALS S.A

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brito, Luis Lincoln, US 30 618
Geall, Andrew Carlsbad, US 92 3348
O'Hagan, Derek Winchester, US 138 2360
Singh, Manmohan Cary, US 101 2144

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