SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

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United States of America Patent

SERIAL NO

15070358

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Abstract

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The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the Serpinc1 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of Serpinc1 and methods of treating subjects having a bleeding disorder, such as a hemophilia.

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Patent Owner(s)

Patent OwnerAddress
GENZYME CORPORATION50 BINNEY STREET CAMBRIDGE MA 02142

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akinc, Akin Needham, US 113 3427
Bettencourt, Brian Groton, US 134 658
Charisse, Klaus Acton, US 73 449
Foster, Donald Attleboro, US 35 131
Kuchimanchi, Satyanarayana Acton, US 61 396
Maier, Martin Belmont, US 260 4382
Manoharan, Muthiah Weston, US 491 18658
Milstein, Stuart Arlington, US 133 755
Rajeev, Kallanthottathil G Wayland, US 260 8660
Sehgal, Alfica Medford, US 46 123
Toudjarska, Ivanka Meford, US 32 120

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