Treatment of skeletal voids with implantable substrate hydrated with bone marrow concentrate
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United States of America Patent
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Aug 25, 2020
Grant Date -
Sep 22, 2016
app pub date -
May 30, 2016
filing date -
Oct 23, 2014
priority date (Note) -
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Abstract
The invention is directed to a bone void filler comprising a scaffold or matrix. The scaffold or matrix may include a porous inorganic matrix component and/or a 3D-printed implantable device. The bone void filler may include a cellular component containing cells, some of which are capable of making extracellular matrix resembling native bone tissue. The bone void filler may include an organic matrix, such as, an organic biopolymer that aids in cell retention and renders the scaffold or matrix moldable. The bone void filler may include growth factors and/or cytokines. The bone void filler may include a clotting agent.
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