COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
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United States of America Patent
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Issued Date -
Sep 22, 2016
app pub date -
Mar 18, 2016
filing date -
Mar 18, 2016
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Abandoned
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Abstract
The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors.
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