METHOD FOR PRODUCING ACYL AMINO ACIDS

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United States of America Patent

APP PUB NO 20160272950A1
SERIAL NO

14915012

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Abstract

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The present invention relates to a cell expressing an amino acid-N-acyl-transferase, which is preferably recombinant, and an acyl-CoA synthetase, which is preferably recombinant, wherein the cell has a reduced fatty acid degradation capacity, a method for producing acyl amino acids, comprising the step contacting an amino acid and an acyl CoA in the presence of an amino acid-N-acyl-transferase, which is preferably isolated and/or recombinant, wherein the amino acid-N-acyl-transferase is preferably a human amino acid-N-acyl-transferase, or culturing the cell and a reaction mixture comprising an amino acid-N-acyl-transferase, which is preferably isolated and/or recombinant, an acyl-CoA synthetase, which is preferably isolated and/or recombinant, an amino acid and either a fatty acid-CoA or a fatty acid and an acyl-CoA-synthase.

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Patent Owner(s)

Patent OwnerAddress
EVONIK DEGUSSA GMBHRELLINGHAUSER STRASSE 1-11 ESSEN 45128

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CORTHALS, Jasmin Bochum, DE 3 26
GRAMMANN, Katrin Oer-Erkenschwick, DE 8 109
HAAS, Thomas Muenster, DE 183 2419
OLFERT, Maik Recklinghausen, DE 2 11
POTGRAVE, Nicole Dorsten, DE 1 8
REINECKE, Liv Essen, DE 9 169
SCHAFFER, Steffen Herten, DE 56 860
WOLTER, Jan Duesseldorf, DE 14 25

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