BISCATIONIC AND TRISCATIONIC AMPHIPHILES AS ANTIMICROBIAL AGENTS

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United States of America Patent

APP PUB NO 20160278375A1
SERIAL NO

15034404

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides an antimicrobial composition including a compound which is a biscationic or triscationic amphiphile, and the method of making such an antimicrobial composition, and the method of using such a compound or composition for antimicrobial use. The antimicrobial composition can include a compound having the formula (I) wherein R is a methylene group unsubstituted or optionally substituted, s is an integer in the range from 1 to 6, R1, R2, R3 or R4 is H or a C1-4 alkyl unsubstituted or optionally substituted, X is a halogen, m and n are integers in the range from 5 to 25, and m is not equal to n. Alternatively, the antimicrobial composition can comprise a compound having the formula (III) or (IV) wherein R1, R2, R3, R4 R5, or R6 is H or a C1-4 alkyl unsubstituted or optionally substituted, X or Y is a halogen, and m and n are integers in the range from 5 to 25.

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Patent Owner(s)

Patent OwnerAddress
VILLANOVA UNIVERSITY800 LANCASTER AVENUE VILLANOVA PA 19085

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
MINBIOLE, Kevin Patrick Media, US 3 12
WUEST, William Wallingford, US 3 12

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