System and method for tracking cerebral blood flow in fMRI

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United States of America Patent

PATENT NO 10912470
APP PUB NO 20160287100A1
SERIAL NO

15034792

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Abstract

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A system and method for analyzing blood flow in a subject's brain is provided. In some aspects, the method includes analyzing fMRI data to identify signals related to blood flow, and selecting a zero time lag seed regressor using the identified signals. The method also includes correlating the selected seed regressor to identify a subset of the fMRI data that correlates with the seed regressor and is offset in time, combining the subset of the data to determine a time-delayed regressor, and performing repetitions to obtain a number of time-delayed regressors, where for each repetition, the seed regressor is adjusted using a previous time-delayed regressor. The method further includes analyzing the data using the time-delayed regressors to determine blood delivery from vessels across the brain, and generating a report. In some aspects, a second recursive procedure may be performed using an optimized seed regressor obtained from a first recursive procedure.

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Patent Owner(s)

Patent OwnerAddress
MCLEAN HOSPITAL CORPORATION115 MILL STREET BELMONT MA 03478

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Frederick, Blaise B Belmont, US 1 3
Tong, Yunjie Belmont, US 4 60

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