Method of Fabricating Anticancer Drug Having Doxorubicin Bonded with Gold Nanoparticles

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United States of America Patent

APP PUB NO 20160287723A1
SERIAL NO

14672711

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Albumin and doxorubicin are bonded through reaction. The bonded albumin and doxorubicin are added with a gold-nanoparticles solution for reaction. After being purified with water in a column, the liquid phase of gold-nanoparticles is changed into a phosphate buffer for obtaining an anticancer drug having doxorubicin bonded with gold nanoparticles. Thus, with the high biocompatibility and the big surface areas, gold nanoparticles are used in biological applications and used as carriers for increasing drug accumulation on tumor. The bonding between gold nanoparticles and doxorubicin increases stability of doxorubicin. Besides, doxorubicin has tumor-killing effect for cancer therapy.

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Patent OwnerAddress
INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL EXECUTIVE YUAN R O CTAOYUAN CITY 32546

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Inventor Name Address # of filed Patents Total Citations
Cheng, Chun-Chia Taoyuan City, TW 7 5
Luo, Tsai-Yueh Taoyuan City, TW 21 11

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