Aqueous Systems For The Preparation Of Lipid Based Pharmaceutical Compounds; Compositions, Methods, And Uses Thereof

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United States of America Patent

SERIAL NO

15204826

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Abstract

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The present invention relates to a methods of preparing active compounds complexed with lipids using aqueous systems that are free of organic solvents, and methods of using the complexes, e.g., in treating a disease in a subject. In some embodiments, the present invention comprises a composition comprising a complex comprising at least one active compound, e.g., a polyene antibiotic, an immunosuppressant agent such as tacrolimus or a taxane or taxane derivative, and one or more lipids. In some embodiments, the present invention provides a method comprising preparing a composition comprising a lipid complex comprising at least one active compound and at least one lipid and administering the composition to a subject. In certain embodiments the subject is a mammal. In certain preferred embodiments, the subject is human.

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Patent Owner(s)

Patent OwnerAddress
JINA PHARMACEUTICALS INC28100 NORTH ASHLEY CIRCLE SUITE 103 LIBERTYVILLE IL 60048

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahmad, Ateeq Wadsworth, US 19 102
Ahmad, Imran Wadsworth, US 68 541
Ahmad, Moghis U Wadsworth, US 20 125
Ali, Shoukath M Lake Bluff, US 23 203
Sheikh, Saifuddin Waukegan, US 18 96

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