Dual Targeting siRNA Agents

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United States of America Patent

SERIAL NO

14885342

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Abstract

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The invention relates to dual targeting siRNA agents targeting a PCSK9 gene and a second gene, and methods of using dual targeting siRNA agents to inhibit expression of PCSK9 and to treat PCSK9 related disorders, e.g., hyperlipidemia.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142-1110

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Charisse, Klaus Acton, US 73 449
Fitzgerald, Kevin Brookline, US 209 2389
Frank-Kamenetsky, Maria Brookline, US 50 1080

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