SINGLE CELL GENE EXPRESSION FOR DIAGNOSIS, PROGNOSIS AND IDENTIFICATION OF DRUG TARGETS

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United States of America Patent

APP PUB NO 20160312302A1
SERIAL NO

15135702

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Abstract

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Methods are provided for diagnosis and prognosis of disease by analyzing expression of a set of genes obtained from single cell analysis. Classification allows optimization of treatment, and determination of whether on whether to proceed with a specific therapy, and how to optimize dose, choice of treatment, and the like. Single cell analysis also provides for the identification and development of therapies which target mutations and/or pathways in disease-state cells.

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Patent Owner(s)

Patent OwnerAddress
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYBUILDING 170 3RD FLOOR MAIN QUAD P O BOX 20386 STANFORD CA 94305

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Clarke, Michael F Palo Alto, US 65 2950
Dalerba, Piero D New York, US 7 264
Diehn, Maximilian Stanford, US 28 667
Kalisky, Tomer Palo Alto, US 5 261
Leyrat, Anne San Carlos, US 2 200
Liu, Huiping Chicago, US 18 285
Quake, Stephen R Stanford, US 279 17346
Wang, Jianbin Beijing, CN 53 1130

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