Quantitative assessment of biological impact using overlap methods

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United States of America Patent

APP PUB NO 20160321393A1
SERIAL NO

15012447

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Abstract

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Scores for particular network models (those having a source node connected to a set of measurable downstream nodes via causal edges) are computed across multiple networks by accounting for an overlap between these models in a manner that reduces cross-network redundancy and increases the specificity of the network models for the network in which they are found. According to another aspect, a meta-network model is created for networks by accounting for the occurrence of network models that are found in multiple networks in a manner that reduces the redundancy across networks and that increases the specificity of the network model score. Preferably, this process provides additional weighting factors for each node in the network model.

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Patent Owner(s)

Patent OwnerAddress
SELVENTA INCONE ALEWIFE CENTER CAMBRIDGE MA 02140

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Drubin, David Cambridge, US 4 2
Frushour, Brian Cambridge, US 2 1
Thomson, Ty Matthew Arlington, US 10 8
Vasilyev, Dmitry Somerville, US 14 139

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