POLYMER-BASED COMPOSITIONS FOR EXTENDED RELEASE OF PROTEINS
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United States of America Patent
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Issued Date -
Nov 10, 2016
app pub date -
Dec 30, 2014
filing date -
Dec 31, 2013
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Abstract
The present application is directed to poly(orthoester)-based formulations that are effective for the sustained delivery of one or more therapeutic proteins. The formulations additionally maintain the stability and bioactivity (i.e., significantly minimize the degradation and/or aggregation) of the protein contained in the poly(orthoester) matrix during preparation, storage and release.
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