MICROFLUIDIC BIOREACTOR WITH MODULAR DESIGN FOR SYNTHESIZING CELL METABOLITES, METHOD FOR USING SAME, AND USE THEREOF
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United States of America Patent
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Issued Date -
Nov 10, 2016
app pub date -
Dec 17, 2014
filing date -
Dec 20, 2013
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Abstract
A microfluidic bioreactor includes at least two modules each having a cavity, each of which is divided by a membrane into a cell chamber for receiving cells and a material chamber through which a liquid solution comprising at least one additive and cell metabolites can flow, wherein each membrane has a reaction region in which the membrane is permeable at least in part to the solution comprising the at least one additive and the cell metabolites, and a fluid conducting system for the liquid solution comprising the at least one additive and the cell metabolites, which fluid conducting system connects the material chambers together at least one of in series or in parallel. Unidirectional flow through the fluid conducting system is ensured.
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