METHOD FOR INCREASING THE BIOAVAILABILITY OF INHALED COMPOUNDS
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United States of America Patent
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Nov 17, 2016
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Jan 16, 2015
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Jan 16, 2015
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Abstract
The present invention relates to a compound comprising one or more PEG moieties, wherein said compound is a therapeutic agent active for treating a respiratory disease. The present invention also relates to the use of a PEGylated therapeutic agent for treating a respiratory disease. Another object of the invention is a method for enhancing the bioavailability of a therapeutic agent, for enhancing the pulmonary residency of a therapeutic agent and/or for reducing the pulmonary clearance of a therapeutic agent, wherein said methods comprise the PEGylation of the therapeutic agent.
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