ARYLQUINOLINE, ARYLQUINOLONE AND ARYLTHIOQUINOLONE DERIVATIVES AND USE THEREOF TO TREAT CANCER

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United States of America Patent

APP PUB NO 20160332971A1
SERIAL NO

15152185

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Abstract

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Arylquinoline derivatives and their use for treating cancer or cancer metastasis is disclosed. The compounds of the subject technology promote cells to secrete a pro-apoptotic tumor suppressor, i.e., prostate apoptosis response-4 (Par-4), which in turn promote apoptosis in cancer cells or metastatic cells.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION311 MAIN BUILDING LEXINGTON KY 40506

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BURIKHANOV, Ravshan Lexington, US 5 5
LIU, Chunming Lexington, US 39 235
RANGNEKAR, Vivek M Lexington, US 7 8
SVIRIPA, Vitaliy M Lexington, US 8 11
WATT, David S Lexington, US 15 12
ZHANG, Wen Lexington, US 354 1596

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