USE OF PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXIGENASE (PAM) FOR C-TERMINAL AMIDATION

United States of America Patent

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Jun 17, 2016
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Dec 20, 2013

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Abstract

One aspect as reported herein is a method for in vivo C-terminal amidation of a polypeptide characterized in that both the polypeptide (to be amidated) and human peptidylglycine alpha-amidating monooxigenase (PAM) are recombinantly co-expressed in a mammalian cell.

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Patent Owner	Address
HOFFMANN-LA ROCHE INC	150 CLOVE ROAD OVERLOOK AT GREAT NOTCH SUITE 8 LITTLE FALLS NJ 07424

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C12P:FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESI....

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Inventor Name	Address	# of filed Patents	Total Citations
HOFFMANN, EIKE	HERRSCHING a. AMMERSEE, DE	26	569
TIEFENTHALER, GEORG	SINDELSDORF, DE	38	157

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USE OF PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXIGENASE (PAM) FOR C-TERMINAL AMIDATION

Number of patents in Portfolio can not be more than 2000

United States of America Patent

15185477

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15185477

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