FORMULATIONS OF L-ORNITHINE PHENYLACETATE

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United States of America Patent

SERIAL NO

15133087

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Abstract

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Some embodiments of the present application are directed to oral formulations of L-ornithine phenylacetate and methods of preparing the same. These oral formulations offer alternative administration route than the standard intravenous administration of L-ornithine phenylacetate for treating hyperammonemia in patients having various acute and chronic liver diseases and disorders, for example, acute liver failure, liver cirrhosis, liver decompensation, portal hypertension, hepatic encephalopathy, or patients with urea cycle disorders.

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Patent Owner(s)

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OCERA THERAPEUTICS LLC675 MCDONNELL BLVD HAZELWOOD MO 63042

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bernstein, James Raleigh, US 5 63
Coffin, Mark Durham, US 4 23
Goodson, Gary Raleigh, US 2 22
Ruettimann, Kenneth Raleigh, US 2 22
Wang, Laurene Chapel Hill, US 7 40

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