Device and method for sampling bodily fluid for medical analytes in ultra low concentrations

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United States of America Patent

PATENT NO 10006841
SERIAL NO

15190634

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Trapping devices and methods are provided for capturing a medical analyte, in blood or another biological fluid. The device may include a structural substrate and a binding agent, such as an antibody, affixed to the structural substrate, wherein the binding agent is capable of binding or attaching with a medical analyte, such as a viral particle, and the device is configured for placement in a biological cavity or vessel (containing a biological fluid) in a patient. The trapping device, which may be in a twisted coil shape, is configured to trap at least some of the medical analyte, such a viral particle, present in the biological fluid. The method may include deploying a trapping device into the patient's blood vessel; after a period following the deployment, removing the trapping device from the biological cavity or blood vessel; and then analyzing the trapping device for the presence of the medical analyte.

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Patent Owner(s)

  • MASSACHUSETTS INSTITUTE OF TECHNOLOGY; LAHEY CLINIC FOUNDATION, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cima, Michael J Winchester, US 150 9578
Ekchian, Gregory J Belmont, US 6 74
Flacke, Sebastian Nahant, US 3 17
Gordon, Fredric D Newton, US 2 15
Liu, Vincent H Cambridge, US 2 15
Vassiliou, Christophoros C Cambridge, US 6 27
Wald, Christoph Nahant, US 2 15

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