On-column viral inactivation methods

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United States of America Patent

PATENT NO 10611794
APP PUB NO 20160347788A1
SERIAL NO

15024988

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Abstract

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The present invention is directed to a method of inactivating virus that is present during production of a polypeptide of interest. In particular, the present invention is directed to a method of on-column virus inactivation using a low pH and high salt wash solution that effectively inactivates viruses with minimum recovery loss of the polypeptide.

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Patent Owner(s)

  • BIOVERATIV THERAPEUTICS INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bolton, Glen Boston, US 5 4
Selvitelli, Keith Sutton, US 5 20

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