ANG-(1-7) derivative oligopeptides and methods for using and producing the same

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United States of America Patent

PATENT NO 9670251
APP PUB NO 20160347794A1
SERIAL NO

15134073

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Abstract

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The present invention provides oligopeptides, in particular, Ang-(1-7) derivatives, and methods for using and producing the same. In one particular embodiment, oligopeptides of the invention have higher blood-brain barrier penetration and/or in vivo half-life compared to the native Ang-(1-7), thereby allowing oligopeptides of the invention to be used in a wide variety of clinical applications including in treatment of cognitive dysfunction and/of impairment.

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Patent Owner(s)

  • THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hay, Meredith Tucson, US 15 8
Jones, Evan Tucson, US 60 725
Konhilas, John Tucson, US 21 39
Polt, Robin L Tucson, US 24 50

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