MODULATION OF TRANSTHYRETIN EXPRESSION

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United States of America Patent

SERIAL NO

15092476

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Abstract

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Compounds, compositions and methods are provided for modulating the expression of transthyretin. The compositions comprise oligonucleotides, targeted to nucleic acid encoding transthyretin. Methods of using these compounds for modulation of transthyretin expression and for diagnosis and treatment of diseases and conditions associated with expression of transthyretin are provided.

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Patent Owner(s)

Patent OwnerAddress
IONIS PHARMACEUTICALS INCCARLSBAD CA 92010

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown-Driver, Vickie L Solana Beach, US 27 325
Jain, Ravi Fremont, US 177 4378

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