METHODS AND COMPOSITIONS FOR CHROMOSOME MAPPING
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United States of America Patent
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Dec 15, 2016
app pub date -
Sep 26, 2014
filing date -
Sep 26, 2013
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Abstract
Provided herein are improved methods, compositions, and kits for analysis of nucleic acids. The improved methods, compositions, and kits can enable directional chromosome mapping e.g., using chromosome phasing/haplotyping. The improved methods, compositions, and kits can also enable copy number estimation of a nucleic acid in a sample. Also provided herein are methods, compositions, and kits for determining the linkage of two or more copies of a target nucleic acid in a sample (e.g., whether the two or more copies are on the same chromosome or different chromosomes) or for phasing alleles.
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