CELLULAR RESPONSE ASSAY FOR BIOFLUID BIOMARKER DISCOVERY AND DETECTION

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United States of America Patent

APP PUB NO 20160370354A1
SERIAL NO

15252039

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides a method to detect an abnormal condition or disease state by assessing a characteristic response pattern of responder cells to indicators contained in a biological fluid of a subject. A characteristic disease-associated pattern can be obtained by determining the response pattern of responder cells to that of bodily fluids or fractions thereof from subjects known to exhibit a particular abnormal condition optionally comparing said pattern to such pattern elicited by fluids or fractions from normal subjects and identifying elements that differ. The identified elements constitute a characteristic or differential pattern which can then be used to identify the presence or stage of a disease in a test subject.

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Patent Owner(s)

Patent OwnerAddress
INSTITUTE FOR SYSTEMS BIOLOGY401 TERRY AVE N SEATTLE WA 98109

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AITCHISON, John David Seattle, US 4 1
MILLER, Leslie Rae Seattle, US 3 1
SMITH, Jennifer Joy Seattle, US 4 1

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