Methods for beaming

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United States of America Patent

PATENT NO 10150991
APP PUB NO 20160376645A1
SERIAL NO

15174427

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Abstract

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Improvements on the basic method used for BEAMing increase sensitivity and increase the signal-to-noise ratio. The improvements have permitted the determination of intrinsic error rates of various DNA polymerases and have permitted the detection of rare and subtle mutations in DNA isolated from plasma of cancer patients.

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Patent Owner(s)

  • THE JOHNS HOPKINS UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Diehl, Frank Schortens, DE 18 235
Kinzler, Kenneth W Baltimore, US 281 4771
Li, Meng San Francisco, US 405 1864
Vogelstein, Bert Baltimore, US 323 6299

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