Methods and apparatus for preparing aqueous specimens for electron microscopy using volatile surfactants

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United States of America Patent

PATENT NO 10309881
APP PUB NO 20170004953A1
SERIAL NO

15194777

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Abstract

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This disclosure provides systems, methods, and apparatus related to the preparation of electron microscopy specimens. In one aspect, a method includes providing an electron microscopy grid. An aqueous suspension including an electron microscopy sample is deposited on the electron microscopy grid. A portion of the aqueous suspension is removed from the electron microscopy grid. A volatile surfactant is contacted to the aqueous suspension. A thickness of aqueous suspension is allowed to decrease over a period of time. The aqueous suspension is then frozen.

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Patent Owner(s)

  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Glaeser, Robert M Berkeley, US 7 45
Han, Bong-Gyoon Castro Valley, US 4 15

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