COMPOSITIONS AND METHODS FOR BORON NEUTRON CAPTURE THERAPY
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United States of America Patent
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Jan 12, 2017
app pub date -
Feb 23, 2015
filing date -
Feb 21, 2014
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Abstract
Provided herein are compositions and methods for boron neutron capture therapy. In particular, the disclosure relates to therapy using liposomal Na3[1-(2′-B10H9)-2-NH3B10H8] and K[nido-7-CH3(CH2)15-7,8-C2B9H11] sources. A composition for boron neutron capture therapy, comprising a liposome having an aqueous core and an encapsulating bilayer, wherein the aqueous core comprises Na3[1-(2′-B10H9)-2-NH3B10H8] (TAC) and the encapsulating bilayer comprises K[nido-7-CH3(CH2)15-7,8-C2B9H11] (MAC) is also provided.
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