CYP-eicosanoid derivatives

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United States of America Patent

PATENT NO 11130772
APP PUB NO 20170008918A1
SERIAL NO

15113139

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Abstract

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The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.

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Patent Owner(s)

  • MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN; BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Falck, John Russell Dallas, US 5 8
Fischer, Robert Berlin, DE 89 1359
Konkel, Anne Berlin, DE 4 1
Mueller, Dominik Berlin, DE 14 13
Schunck, Wolf-Hagen Berlin, DE 6 8
Wallukat, Gerd Berlin, DE 16 26

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