COMPOSITIONS AND METHODS FOR DETECTING SNP(S) ASSOCIATED WITH DIABETES

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United States of America Patent

SERIAL NO

15203708

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Abstract

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In one aspect, provided herein are set of primers and use of the same for the detection of SNPs associated with diabetes. In certain embodiments, the primers used to detect SNP sites associated with diabetes comprise Primer Set 1 to Primer Set 47. The experiments show: the genotyping results of the SNP sites associated with diabetes can be accurately detected by the primers disclosed herein, and the risk of individuals can be comprehensively evaluated and the result is more accurate than the single site analysis. In addition, SNPs disclosed herein are verified as associated with type 2 diabetes and its complications, which are especially suitable for the prevention and individualized treatment for type 2 diabetes in East Asian, for example, in China.

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Patent Owner(s)

Patent OwnerAddress
TSINGHUA UNIVERSITYQINGHUA PARK HAIDIAN DISTRICT BEIJING CITY 100084
CAPITALBIO CORPORATIONCHANGPING DISTRICT BEIJING 102206
CAPITALBIO EHEALTH SCIENCE & TECHNOLOGY (BEIJING) CO LTD18 LIFE SCIENCE PARKWAY CHANGPING DISTRICT BEIJING 102206
SHANGHAI SIXTH PEOPLE'S HOSPITALNO 600 YISHAN ROAD XUHUI DISTRICT SHANGHAI 200233

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHENG, Jing Beijing, CN 184 3034
HU, Cheng Beijing, CN 73 445
JIA, Weiping Beijing, CN 6 16
SHAO, Lin Beijing, CN 36 163
SUN, Yimin Beijing, CN 30 62
XIE, Lan Beijing, CN 50 127

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