AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER AND OTHER DISORDERS

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United States of America Patent

APP PUB NO 20170029468A1
SERIAL NO

15297688

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP-dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition including Crohn's disease and ulcerative colitis, and cancer.

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Patent Owner(s)

Patent OwnerAddress
SYNERGY PHARMACEUTICALS INCNEW YORK NY 10170

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
SHAILUBHAI, Kunwar Audubon, US 96 1112

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