ANTIBODY CONSTRUCTS FOR MSLN AND CD3
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United States of America Patent
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Feb 2, 2017
app pub date -
Aug 1, 2016
filing date -
Jul 31, 2015
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Abstract
The present invention relates to a bispecific antibody construct comprising a first binding domain which binds to human MSLN on the surface of a target cell and a second binding domain which binds to human CD3 on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
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