Stable proteins and methods for designing same

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United States of America Patent

PATENT NO 10468119
APP PUB NO 20170032079A1
SERIAL NO

15259311

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Abstract

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A method for designing and selecting a protein having a stabilized structure compared to a corresponding wild type protein, and proteins having at least six amino acid substitutions with respect to a corresponding wild type protein, designed for improved thermal stability, improved specific activity and/or improved expression levels, are provided herein.

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Patent Owner(s)

Patent OwnerAddress
YEDA RESEARCH AND DEVELOPMENT CO LTD7610002 REHOVOT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fleishman, Sarel Rehovot, IL 14 9
Goldenzweig, Adi Rehovot, IL 5 0
Tawfik, Dan S Rehovot, IL 18 117

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