extract, fraction of same or compound separated from same for preventing or treating chronic obstructive pulmonary disease (COPD)

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United States of America Patent

PATENT NO 10751378
APP PUB NO 20170035822A1
SERIAL NO

15304316

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Abstract

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The present invention relates to a composition for suppressing chronic obstructive pulmonary disease (COPD) comprising a Pistacia weinmannifolia extract, a fraction thereof, or a compound isolated therefrom and, more particularly, to a pharmaceutical composition for preventing or treating COPD comprising a Pistacia weinmannifolia extract, a fraction thereof, or a compound isolated therefrom; a food composition for preventing or improving COPD, and the compound isolated therefrom. The composition comprising a Pistacia weinmannifolia extract, a fraction thereof, or a compound isolated therefrom, according to the present invention, is not toxic, suppresses the invasion of inflammatory cells into the bronchial tube of a COPD-induced animal model, and effectively suppresses the expression of CXCL-1, TNF-α, or MIP-2. In addition, due to the use of a safety-proven herbal drug as a raw material, the composition of the present invention can resolve various side-effects of existing therapeutic agents for COPD, chronic obstructive bronchitis, chronic bronchiolitis, emphysema, multiple sclerosis, and acute and chronic inflammation, and thus can be effectively used as a composition for preventing, treating and remedying COPD.

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Patent Owner(s)

Patent OwnerAddress
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY125 GWAHAK-RO YUSEONG-GU DAEJEON 34141 34141

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahn, Kyung Seop Daejeon, KR 40 22
Choi, Sang Ho Daejeon, KR 46 170
Jin, Hang Yunnan, CN 171 2884
Kim, Jung Hee Daejeon, KR 34 127
Kim, Seung Hyung Daejeon, KR 7 0
Lee, Joong Ku Daejeon, KR 7 6
Lee, Sang Woo Daejeon, KR 138 937
Li, Wan Yi Yunnan, CN 6 0
Oh, Sei Ryang Daejeon, KR 26 23
Ryu, Hyung Won Daejeon, KR 16 1
Shin, In Sik Daejeon, KR 14 1

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