Methods for modulating angiogenesis of cancers refractory to anti-VEGF treatment

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United States of America Patent

PATENT NO 10294295
APP PUB NO 20170037120A1
SERIAL NO

15100164

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Abstract

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A method for modulating angiogenesis in a cancer or tumor refractory to anti-VEGF, including identifying a cancer cell as being referactory to anti-VEGF, and then contacting the cancer cell refractory to anti-VEGF with an effective amount of an agent that modulates interaction between Gal1 or a Gal1 fragment and the natural binding partner of Gal1 or the Gal1 fragment to thereby modulate angiogenesis.

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Patent Owner(s)

  • INIS BIOTECH LLC; CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET); FUNDACION SALES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cerliani, Juan Pablo Buenos Aires, AR 3 1
Rabinovich, Gabriel Adrian Buenos Aires, AR 3 26
Russo, Diego Omar Croci Buenos Aires, AR 5 23
Salatino, Mariana Buenos Aires, AR 5 23

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