Liposome composition and method for producing same

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United States of America Patent

PATENT NO 10646442
APP PUB NO 20170042810A1
SERIAL NO

15335640

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Abstract

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Provided are a liposome composition which has a practically required long-term preservation stability, and which has a release rate of a drug on the order of several tens of hours due to releasability of a drug being able to be suitably controlled by rendering an inner water phase hyper-osmotic; and a method for producing the same. According to the present invention, it is possible to provide a liposome composition, including liposomes each of which has an inner water phase and an aqueous solution which constitutes an outer water phase and in which the liposomes are dispersed, in which each of the liposomes encapsulates a drug in a dissolved state, an osmotic pressure of the inner water phase is 2-fold to 8-fold relative to the osmotic pressure of the outer water phase, and a release rate of the drug from each of the liposomes is 10%/24 hr to 70%/24 hr in blood plasma at 37° C.; and a method for producing the same.

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Patent Owner(s)

  • FUJIFILM CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Matsumoto, Takeshi Kanagawa, JP 196 2032
Ono, Kohei Kanagawa, JP 55 693
Ono, Makoto Kanagawa, JP 167 2192
Senga, Kyoko Kanagawa, JP 7 22

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