COMBINATION THERAPY FOR THE TREATMENT OF CANCER
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United States of America Patent
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Issued Date -
Mar 16, 2017
app pub date -
Nov 4, 2016
filing date -
Mar 28, 2012
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Abstract
Described are methods and compositions for treating cancer that include a dopamine receptor (DR) antagonist such as thioridazine and a chemotherapeutic agent. Optionally, the chemotherapeutic agent is a DNA synthesis inhibitor such as cytarabine or a microtubule inhibitor such as paclitaxel or docetaxel. The methods and compositions are useful for the treatment of cancers such as acute myeloid leukemia.
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