Modified Natural Killer Cells and Uses Thereof
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United States of America Patent
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Mar 16, 2017
app pub date -
May 14, 2015
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May 15, 2014
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Abstract
The present invention provides, in certain aspects, a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15), and methods for producing such cells. The invention further provides methods of using a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15) to treat cancer in a subject or to enhance expansion and/or survival of NK cells.
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