SYDNONE DERIVATIVES FOR CONJUGATION OF COMPOUNDS OF INTEREST
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United States of America Patent
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Issued Date -
Mar 23, 2017
app pub date -
May 15, 2015
filing date -
May 16, 2014
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Abstract
The present invention relates to a process for the preparation of a first compound of interest C1 functionalized with a sydnone compound and to the corresponding functionalized C1 compound of interest. The present invention also relates to a process for the preparation of a conjugate of two compounds of interest C1 and C2 implying a sydnone compound and to the obtained conjugate. The present invention also relates to a process for preparing a compound of interest C2 comprising a strained alkyne moiety functionalized with a sydnone and to the corresponding functionalized compound of interest C2. It also relates to novel sydnone compounds substituted in position 4, which may be used in the above processes.
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