MULTIVALENT PROBES HAVING SINGLE NUCLEOTIDE RESOLUTION
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United States of America Patent
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Sep 6, 2016
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Sep 3, 2015
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Abstract
The present invention relates to, among other things, polymer strands, probes, compositions, methods, and kits for enabling accurate and robust enzyme- and amplification-free detection of DNA and RNA with single base resolution (e.g., detection of a single nucleotide polymorphism (SNP), an insertion, and a deletion). The compositions, methods, and kits may further provide simultaneous detection of DNA and/or RNA and protein targets.
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