COMBINATIONS COMPRISING BREXPIPRAZOLE OR A SALT THEREOF AND A SECOND DRUG FOR USE IN THE TREATMENT OF A CNS DISORDER

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United States of America Patent

APP PUB NO 20170100395A1
SERIAL NO

15386289

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a medicament having a wider treatment spectrum, causing a fewer side effects and superior in tolerability and safety, as compared to known typical antipsychotic agents and atypical antipsychotic agents. The present invention related to a medicament containing (I) a compound which is 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one or a salt thereof, and (II) at least one drug selected from the group consisting of a mood stabilizer, a serotonin reuptake inhibitor, a norepinephrine reuptake inhibitor, a serotonin and norepinephrine reuptake inhibitor, a noradrenergic and specific serotonergic antidepressant, an antianxiety drug, a tricyclic antidepressant, a tetracyclic antidepressant, an antipsychotic drug and an anti-ADHD drug, in combination.

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Patent Owner(s)

Patent OwnerAddress
OTSUKA PHARMACEUTICAL CO LTDTOKYO JAPAN TOKYO METROPOLIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HIROSE, Tsuyoshi Osaka, JP 44 295
KIKUCHI, Tetsuro Osaka, JP 74 1072
MAEDA, Kenji Osaka, JP 283 3363
TODA, Masafumi Osaka, JP 8 29

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