Methods for screening voltage-gated proteins

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United States of America Patent

PATENT NO 10739354
APP PUB NO 20170115309A1
SERIAL NO

15295436

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Abstract

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In one aspect, the invention relates to a method for identifying a compound which modulates the activity of a voltage-gated protein. In certain embodiments, the voltage gate protein is a voltage-gated ion channel. In certain embodiments, the voltage-gated protein is a voltage sensitive phosphatase. In certain embodiments, the voltage-gated protein used in conjunction with the methods of the invention is modified to altered permeability or voltage sensitivity.

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Patent Owner(s)

Patent OwnerAddress
D E SHAW RESEARCH LLC120 W 45 ST 39TH FL NEW YORK NY 10036

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borhani, David Wayne Hartsdale, US 2 0
Jensen, Morten Østergaard New York, US 9 0
Jogini, Vishwanath Hyderabad, IN 9 18

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