A THERAPEUTIC PROTOCOL FOR TREATING OVARIAN CANCER
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United States of America Patent
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May 4, 2017
app pub date -
May 30, 2014
filing date -
May 30, 2014
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Abstract
The present invention is directed to a pharmaceutical combination for treating proliferative disease comprising a compound of formula (I), or a salt, solvate or prodrug thereof, carboplatin or cisplatin, and gemcitabine. The present invention is further directed to a therapeutic protocol to manage ovarian cancer treatment in a female subject involving the administration of the combination to an ovarian cancer subject with recurrent or persistent ovarian cancer following treatment with platinum-based therapy. Kits comprising the combination as well as the use of the combination in the treatment of a proliferative disease are further contemplated.
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