Compositions and Methods for Inhibiting Expression of Factor V

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United States of America Patent

SERIAL NO

15241025

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Abstract

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The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of Factor V, comprising an antisense strand having a nucleotide sequence which is less that 25 nucleotides in length and which is substantially complementary to at least a part of Factor V. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of Factor V using the pharmaceutical composition; and methods for inhibiting the expression of Factor V in a cell.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142-1110

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Maraganore, John M Charlestown, US 31 356
Vornlocher, Hans-Peter Bayreuth, DE 97 2123

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