Antibody constructs for CD70 and CD3

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United States of America Patent

PATENT NO 10851170
APP PUB NO 20170129961A1
SERIAL NO

15225282

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Abstract

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The present invention relates to a bispecific antibody construct comprising a first binding domain which binds to human CD70 on the surface of a target cell and a second binding domain which binds to human CD3 on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.

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Patent Owner(s)

Patent OwnerAddress
AMGEN INCONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320-1799

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blümel, Claudia Munich, DE 23 323
Deisting, Wibke Munich, DE 3 20
Hoffmann, Patrick Munich, DE 69 1097
Lutterbüse, Ralf Munich, DE 38 334
Nahrwold, Elisabeth Munich, DE 21 201
Nolan-Stevaux, Olivier Millbrae, US 8 37
Panzer, Marc Munich, DE 3 20
Raum, Tobias Munich, DE 92 1685

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