Byosynthetic Production of Acyl Amino Acids
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United States of America Patent
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app pub date -
Apr 28, 2015
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May 23, 2014
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Abandoned
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Abstract
The present invention relates to a cell for producing acyl glycinates wherein the cell is genetically modified to comprise
- at least a first genetic mutation that increases the expression relative to the wild type cell of an amino acid-N-acyl-transferase,at least a second genetic mutation that increases the expression relative to the wild type cell of an acyl-CoA synthetase, andat least a third genetic mutation that decreases the expression relative to the wild type cell of at least one enzyme selected from the group consisting of an enzyme of the glycine cleavage system, glycine hydroxymethyltransferase (GlyA) and threonine aldolase (LtaE).
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