METHOD FOR REDUCING WHITE MATTER LESIONS, WHITE MATTER HYPERINTENSITIES (WMH), LEUKOARAIOSIS OR PERIVENTRICULAR WHITE MATTER DISEASE IN ELDERLY

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United States of America Patent

APP PUB NO 20170157164A1
SERIAL NO

15115487

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Abstract

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The invention pertains to the use of one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof in the manufacture of a composition for treating, preventing or reducing the risk of occurrence of white matter lesions, white matter hyperintensities (WMH), Leukoaraiosis or periventricular white matter disease in elderly not suffering from a neurodegenerative disorder, preferably non-demented elderly and elderly not suffering from Alzheimer's Disease. It was found that with the compositions according to the invention Nogo-A protein levels could be controlled, particularly suppressed or reduced.

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Patent Owner(s)

Patent OwnerAddress
N V NUTRICIAEERSTE STATIONSSTRAAT 186 ZOETERMEER NL-2712 HM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CANSEV, Mehmet Bursa, TR 2 0
HAGEMAN, Robert Johan Joseph Utrecht, NL 100 603
VAN, WIJK Nick Utrecht, NL 3 0

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