METHODS AND COMPOSITIONS FOR ASSAYING THE ACTIVITY OF ONE OR MORE LYSOSOMAL ENZYMES

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United States of America Patent

SERIAL NO

15210766

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Abstract

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Methods and liquid compositions for assaying the activity of one or more lysosomal enzymes in a sample are provided. In some embodiments, the assay is a multiplexed assay for the activities of a plurality of lysosomal enzymes in the sample. The compositions and methods can comprise or employ: one or more metal cations effective for precipitating sulfate ions, one or more metal cations effective for precipitating phosphate ions, a maltase glucoamylase inhibitor, a beta-N-acetylhexosaminidase inhibitor, and one or more surfactants.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF WASHINGTONSEATTLE WA 98195

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barcenas, Rodriguez Mariana Natali Seattle, US 5 2
Gelb, Michael H Seattle, US 25 286
Scott, C Ronald Seattle, US 8 143
Spacil, Zdenek Seattle, US 6 3
Turecek, Frantisek Seattle, US 14 184

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