ANTIBODIES WITH MODIFIED ISOELECTRIC POINTS

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United States of America Patent

APP PUB NO 20170174757A1
SERIAL NO

15444087

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates generally to compositions and methods for altering the isoelectric point of an antibody, and in some cases, resulting in improved plasma pharmacokinetics, e.g. increased serum half-life in vivo.

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Patent Owner(s)

Patent OwnerAddress
XENCOR INC465 NORTH HALSTEAD STREET SUITE 200 PASADENA CA 91107

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bernett, Matthew J Monrovia, US 82 1810
Dahiyat, Bassil I Altadena, US 58 3811
Lazar, Gregory Pacifica, US 19 103

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