HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF

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United States of America Patent

SERIAL NO

15300497

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK535 WEST 116TH STREET 412 LOW MEMORIAL LIBRARY NEW YORK NY 10027

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AMENGUAL, Jennifer Effie Scarsdale, US 9 4
ARANCIO, Ottavio New York, US 34 59
DENG, Shixian White Plains, US 41 114
FIORITO, Jole New York, US 13 9
LANDRY, Donald W New York, US 110 907
O'CONNOR, Owen Anthony Scarsdale, US 6 4
PURGATORIO, Rosa New York, US 6 4

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